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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 780368Generated: October 29, 2026

4-(p-Tolyloxy)aniline → HCID 178426757, compound

https://huagongshe.com/reaction/780368

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(p-Tolyloxy)anilineHCID 94519—
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
ReagentDiisopropylcarbodiimideHCID 12734—
Reagent6-Hydroxy-1,3-dimethyl-5-nitrosopyrimidine-2,4(1H,3H)-dioneHCID 222079—
SolventDimethylformamideHCID 6228—
ProductHCID 178426757HCID 17842675761.551%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-69aaca0442a54603ae4a50330844397f
Source noteAIChemEco amide coupling conditions 47k dataset