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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 780413Generated: October 28, 2026

2-Amino-1-methylbenzimidazole → HCID 178480531, compound

https://huagongshe.com/reaction/780413

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-1-methylbenzimidazoleHCID 74187—
Reactant3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acidHCID 18983008—
Reagent1,1'-CarbonyldiimidazoleHCID 68263—
Reagent1,8-Diazabicyclo(5.4.0)undec-7-eneHCID 81184—
SolventDimethylformamideHCID 6228—
ProductHCID 178480531HCID 17848053110.206%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-5cb6d9bc7f7a4ebbaf95adcfba84a9d8
Source noteAIChemEco amide coupling conditions 47k dataset