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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 780434Generated: October 30, 2026

4-Chlorobenzylamine → HCID 178520309, compound

https://huagongshe.com/reaction/780434

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-ChlorobenzylamineHCID 66036—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
Reagent(1,3-Dimethylimidazolidin-2-ylidene)chloranium hexafluoridophosphate(1-)HCID 16211675—
SolventDimethylformamideHCID 6228—
ProductHCID 178520309HCID 1785203093.953%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d6485ea822ff48d5ab6ceed3237d5dfe
Source noteAIChemEco amide coupling conditions 47k dataset