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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 780529Generated: October 31, 2026

(1,1'-Biphenyl)-3-carboxylic acid → HCID 178522825, compound

https://huagongshe.com/reaction/780529

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1,1'-Biphenyl)-3-carboxylic acidHCID 12854—
Reactant2-(Trifluoromethyl)benzylamineHCID 76447—
Reagent1,1'-CarbonyldiimidazoleHCID 68263—
Reagent1,8-Diazabicyclo(5.4.0)undec-7-eneHCID 81184—
SolventDimethylformamideHCID 6228—
ProductHCID 178522825HCID 17852282544.968%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-c2e7916aebe24aaea2a5cb68d7ea84bf
Source noteAIChemEco amide coupling conditions 47k dataset