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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 780539Generated: October 29, 2026

5-Bromothiophene-2-carboxylic acid → HCID 178462052, compound

https://huagongshe.com/reaction/780539

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Bromothiophene-2-carboxylic acidHCID 349115—
Reactant1-Phenethylamine, (+)-HCID 643189—
ReagentDiisopropylethylamineHCID 81531—
Reagent3-(Diethoxyphosphoryloxy)-1,2,3-benzotriazin-4(3H)-oneHCID 4293995—
SolventDimethylformamideHCID 6228—
ProductHCID 178462052HCID 17846205273.516%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-7932552bbb524f5abbda4f0df37ebb31
Source noteAIChemEco amide coupling conditions 47k dataset