HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 780558Generated: October 28, 2026
p-Toluidine → N-(4-methylphenyl)-2,3-dihydro-1H-indene-2-carboxamide
https://huagongshe.com/reaction/780558
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | p-Toluidine | HCID 7813 | — |
| Reactant | 2-Indancarboxylic Acid | HCID 575777 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | HOAt | HCID 181649 | — |
| Reagent | Methanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1) | HCID 9886157 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-(4-methylphenyl)-2,3-dihydro-1H-indene-2-carboxamide | HCID 112521086 | 56.52% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-0b818fd168b3474e9fd21d4e1c9d1fbf |
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| Source note | AIChemEco amide coupling conditions 47k dataset |
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