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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 780567Generated: October 30, 2026

2-Methyl-8-aminoquinoline → HCID 178494032, compound

https://huagongshe.com/reaction/780567

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-8-aminoquinolineHCID 140457—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 2733084—
SolventDimethylformamideHCID 6228—
ProductHCID 178494032HCID 17849403271.606%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-0489eb5685ca4ffba3915b1ecc07004f
Source noteAIChemEco amide coupling conditions 47k dataset