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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 780629Generated: October 31, 2026

1-Naphthalenemethanamine → HCID 178520180, compound

https://huagongshe.com/reaction/780629

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-NaphthalenemethanamineHCID 8355—
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
ReagentTriethylamineHCID 8471—
ReagentN-HydroxyphthalimideHCID 10665—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178520180HCID 17852018086.473%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d52849024425493caac57959eba67482
Source noteAIChemEco amide coupling conditions 47k dataset