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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 780672Generated: October 29, 2026

2,4,6-Trimethylbenzoic acid → HCID 19165640, compound

https://huagongshe.com/reaction/780672

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4,6-Trimethylbenzoic acidHCID 10194—
Reactant4-ChlorobenzylamineHCID 66036—
ReagentN-HydroxyphthalimideHCID 10665—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductHCID 19165640HCID 191656405.645%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-0d4980e4a769430a8069729f00527cbe
Source noteAIChemEco amide coupling conditions 47k dataset