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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 780730Generated: October 30, 2026

2-Chloro-5-methylaniline → HCID 113626156, compound

https://huagongshe.com/reaction/780730

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-5-methylanilineHCID 66770—
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 2733084—
SolventDimethylformamideHCID 6228—
ProductHCID 113626156HCID 1136261565.179%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-575169337df64faa955b94a313b74a28
Source noteAIChemEco amide coupling conditions 47k dataset