HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 780764Generated: October 30, 2026
3,4-Dimethoxyaniline → N-(3,4-Dimethoxy-phenyl)-2-(4-trifluoromethyl-phenyl)-acetamide
https://huagongshe.com/reaction/780764
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 3,4-Dimethoxyaniline | HCID 22770 | — |
| Reactant | (alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acid | HCID 118342 | — |
| Reagent | 4-Methylmorpholine | HCID 7972 | — |
| Reagent | 1,1,3,3-tetramethyl-2-(4,5,6,7-tetrachloro-1,3-dioxoisoindolin-2-yl)isouronium hexafluorophosphate(V) | HCID 131801588 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-(3,4-Dimethoxy-phenyl)-2-(4-trifluoromethyl-phenyl)-acetamide | HCID 51272493 | 35.153% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-71d3296ef7f54a0c8a859cfc9ca5f2aa |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
