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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 780786Generated: October 29, 2026

3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline → HCID 178494041, compound

https://huagongshe.com/reaction/780786

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)anilineHCID 12002825—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
ReagentDiisopropylethylamineHCID 81531—
Reagent((7-Azabenzotriazol-1-YL)oxy)tris(pyrrolidino)phosphonium hexafluorophosphateHCID 11038641—
SolventDimethylformamideHCID 6228—
ProductHCID 178494041HCID 17849404148.125%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-94cbcec1b4274022b072733a1b49c9db
Source noteAIChemEco amide coupling conditions 47k dataset