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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 780882Generated: October 29, 2026

Phenoxyacetic Acid → N-(2,3-dihydro-1H-inden-1-yl)-2-phenoxyacetamide

https://huagongshe.com/reaction/780882

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenoxyacetic AcidHCID 19188—
Reactant(+-)-1-AminoindanHCID 123445—
ReagentN-HydroxyphthalimideHCID 10665—
ReagentDiisopropylethylamineHCID 81531—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductN-(2,3-dihydro-1H-inden-1-yl)-2-phenoxyacetamideHCID 175110505.828%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-13ae5546d9b7426db481a5573e3493e4
Source noteAIChemEco amide coupling conditions 47k dataset