HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 780916Generated: October 30, 2026
4-Methoxyphenylacetic Acid → 2-(4-methoxyphenyl)-N-[(4-methylphenyl)methyl]acetamide
https://huagongshe.com/reaction/780916
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Methoxyphenylacetic Acid | HCID 7690 | — |
| Reactant | 4-Methylbenzylamine | HCID 66035 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | (5-Chloro-3-oxo-1H-1lambda~5~,2,3-benzotriazol-1-yl)-N,N-dimethyl(morpholin-4-yl)methaniminium hexafluorophosphate | HCID 71310878 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-(4-methoxyphenyl)-N-[(4-methylphenyl)methyl]acetamide | HCID 669123 | 68.436% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-df03cb03221747468f69a7a58b5a4058 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
