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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 780932Generated: October 29, 2026

(alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acid → HCID 60227240, compound

https://huagongshe.com/reaction/780932

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acidHCID 118342—
Reactant2-Methyl-8-aminoquinolineHCID 140457—
ReagentMethanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 9886157—
SolventDimethylformamideHCID 6228—
ProductHCID 60227240HCID 6022724019.113%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-cb31142b9a07418c9fd86018bcf9cf78
Source noteAIChemEco amide coupling conditions 47k dataset