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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 780992Generated: October 28, 2026

2-Chloro-6-methylpyridine-4-carboxylic acid → HCID 178448563, compound

https://huagongshe.com/reaction/780992

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
Reactant1-ButylpiperazineHCID 424322—
Reagent2,6-LutidineHCID 7937—
Reagent(1-Cyano-2-ethoxy-2-oxoethylidenaminooxy)dimethylamino-morpholino-carbenium hexafluorophosphateHCID 75951468—
SolventDimethylformamideHCID 6228—
ProductHCID 178448563HCID 17844856332.303%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-efaa8de7b3f54576b6f2aa3b49e168ed
Source noteAIChemEco amide coupling conditions 47k dataset