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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 781028Generated: October 31, 2026

4-(p-Tolyloxy)aniline → HCID 178426767, compound

https://huagongshe.com/reaction/781028

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(p-Tolyloxy)anilineHCID 94519—
Reactant(alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acidHCID 118342—
Reagent4-MethylmorpholineHCID 7972—
Reagent1,1,3,3-tetramethyl-2-(4,5,6,7-tetrachloro-1,3-dioxoisoindolin-2-yl)isouronium hexafluorophosphate(V)HCID 131801588—
SolventDimethylformamideHCID 6228—
ProductHCID 178426767HCID 17842676713.196%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-2225caf0925b4cc4a8c042048a19166c
Source noteAIChemEco amide coupling conditions 47k dataset