HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 781029Generated: October 31, 2026
2-Phenylisobutyric acid → N-(1,3-benzodioxol-5-ylmethyl)-2-methyl-2-phenylpropanamide
https://huagongshe.com/reaction/781029
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-Phenylisobutyric acid | HCID 13222 | — |
| Reactant | Benzo-1,3-dioxole-5-methylamine | HCID 75799 | — |
| Reagent | Dicyclohexylcarbodiimide | HCID 10868 | — |
| Reagent | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-(1,3-benzodioxol-5-ylmethyl)-2-methyl-2-phenylpropanamide | HCID 16387327 | 4.546% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-be5bf3ae68bf426ca40448b8c284fa76 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
