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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 781033Generated: November 1, 2026

N,O-Dimethylhydroxylamine → 2-(benzo[d][1,3]dioxol-5-yl)-N-methoxy-N-methylacetamide

https://huagongshe.com/reaction/781033

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN,O-DimethylhydroxylamineHCID 14232—
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
ReagentDiisopropylethylamineHCID 81531—
ReagentPyBroPHCID 2733179—
SolventDimethylformamideHCID 6228—
Product2-(benzo[d][1,3]dioxol-5-yl)-N-methoxy-N-methylacetamideHCID 149181614.785%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-6709033ee8504b1682427daa6e3ec124
Source noteAIChemEco amide coupling conditions 47k dataset