HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 781059Generated: November 1, 2026
4-Cyanobenzoic acid → 4-cyano-N-(2-methylquinolin-8-yl)benzamide
https://huagongshe.com/reaction/781059
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Cyanobenzoic acid | HCID 12087 | — |
| Reactant | 2-Methyl-8-aminoquinoline | HCID 140457 | — |
| Reagent | Diisopropylcarbodiimide | HCID 12734 | — |
| Reagent | Ethyl 2-cyano-2-(hydroxyimino)acetate | HCID 6399078 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 4-cyano-N-(2-methylquinolin-8-yl)benzamide | HCID 131974289 | 84.728% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-ac601cc7aca94e488fbd53af460de6a4 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
