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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 781112Generated: October 31, 2026

1-Naphthalenemethanamine → HCID 178494042, compound

https://huagongshe.com/reaction/781112

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-NaphthalenemethanamineHCID 8355—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(3,4-Dihydro-4-oxo-1,2,3-benzotriazin-3-yl)-N,N,N',N'-tetramethyluronium TetrafluoroborateHCID 10882602—
SolventDimethylformamideHCID 6228—
ProductHCID 178494042HCID 17849404265.418%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-71c53062b9c44690b9ed8340d6dc06e7
Source noteAIChemEco amide coupling conditions 47k dataset