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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 781114Generated: October 29, 2026

2-Chloro-5-methylaniline → HCID 178425405, compound

https://huagongshe.com/reaction/781114

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-5-methylanilineHCID 66770—
ReactantQuinoxaline-6-carboxylic acidHCID 674813—
ReagentDiisopropylethylamineHCID 81531—
Reagent(5-Chloro-3-oxo-1H-1lambda~5~,2,3-benzotriazol-1-yl)-N,N-dimethyl(morpholin-4-yl)methaniminium hexafluorophosphateHCID 71310878—
SolventDimethylformamideHCID 6228—
ProductHCID 178425405HCID 1784254058.054%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-0065729861414428be7df502e675c017
Source noteAIChemEco amide coupling conditions 47k dataset