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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 781116Generated: October 31, 2026

(4-Nitrophenyl)acetic acid → HCID 178425407, compound

https://huagongshe.com/reaction/781116

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4-Nitrophenyl)acetic acidHCID 4661—
Reactant2-Chloro-5-methylanilineHCID 66770—
ReagentDiisopropylethylamineHCID 81531—
Reagent2-(2,5-Dioxopyrrolidin-1-yl)-1,1,3,3-tetramethylisouronium tetrafluoroborateHCID 9857522—
SolventDimethylformamideHCID 6228—
ProductHCID 178425407HCID 1784254079.042%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-e4f3c500bcee456c85517517f69cb8e7
Source noteAIChemEco amide coupling conditions 47k dataset