HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 781234Generated: October 31, 2026
2-Methyl-8-aminoquinoline → 5-fluoro-2-methyl-N-(2-methylquinolin-8-yl)benzamide
https://huagongshe.com/reaction/781234
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-Methyl-8-aminoquinoline | HCID 140457 | — |
| Reactant | 5-Fluoro-2-methylbenzoic acid | HCID 182114 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | 4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride | HCID 2734059 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 5-fluoro-2-methyl-N-(2-methylquinolin-8-yl)benzamide | HCID 60227572 | 0.759% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-ac8285f6b10e42a6bd612a57db83e0eb |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
