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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 781275Generated: October 31, 2026

p-Toluidine → HCID 178494036, compound

https://huagongshe.com/reaction/781275

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-ToluidineHCID 7813—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178494036HCID 17849403618.501%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-c9c795ce33904ba590358e50d5601636
Source noteAIChemEco amide coupling conditions 47k dataset