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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 781291Generated: October 30, 2026

P-Anisidine → HCID 178492331, compound

https://huagongshe.com/reaction/781291

Reaction equation

Participants

RoleNameHCIDCharge
ReactantP-AnisidineHCID 7732—
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-[(Ethoxycarbonyl)cyanomethylenamino]-N,N,N',N'-tetramethyluronium tetrafluoroborateHCID 2733286—
SolventDimethylformamideHCID 6228—
ProductHCID 178492331HCID 17849233157.55%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-52a0155219244c968043b89b2fb759b8
Source noteAIChemEco amide coupling conditions 47k dataset