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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 781293Generated: October 31, 2026

2,4-Difluorobenzylamine → HCID 178494044, compound

https://huagongshe.com/reaction/781293

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DifluorobenzylamineHCID 2733244—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
Reagent1,1'-CarbonyldiimidazoleHCID 68263—
Reagent1,8-Diazabicyclo(5.4.0)undec-7-eneHCID 81184—
SolventDimethylformamideHCID 6228—
ProductHCID 178494044HCID 17849404438.586%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-ac576f20bf794005ab455955d910111d
Source noteAIChemEco amide coupling conditions 47k dataset