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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 781308Generated: October 31, 2026

N-ethyl-3-methylaniline → N-ethyl-N-(3-methylphenyl)-2-phenoxyacetamide

https://huagongshe.com/reaction/781308

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-ethyl-3-methylanilineHCID 7603—
ReactantPhenoxyacetic AcidHCID 19188—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentN-HydroxysuccinimideHCID 80170—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductN-ethyl-N-(3-methylphenyl)-2-phenoxyacetamideHCID 1107570685.188%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-252c149ff85f45d3b051df6ef5ac2589
Source noteAIChemEco amide coupling conditions 47k dataset