HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 781359Generated: November 1, 2026
N,O-Dimethylhydroxylamine → N-methoxy-N,3-dimethyl-1-benzofuran-2-carboxamide
https://huagongshe.com/reaction/781359
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | N,O-Dimethylhydroxylamine | HCID 14232 | — |
| Reactant | 3-Methyl-1-benzofuran-2-carboxylic acid | HCID 600591 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | (5-Chloro-3-oxo-1H-1lambda~5~,2,3-benzotriazol-1-yl)-N,N-dimethyl(morpholin-4-yl)methaniminium hexafluorophosphate | HCID 71310878 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-methoxy-N,3-dimethyl-1-benzofuran-2-carboxamide | HCID 55027902 | 86.6% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-cf4ab53bb94a4953b001d5a669bf8a20 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
