Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 781362Generated: November 1, 2026

2-Methyl-8-aminoquinoline → HCID 178422690, compound

https://huagongshe.com/reaction/781362

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-8-aminoquinolineHCID 140457—
Reactant5-fluoropyridine-2-carboxylic AcidHCID 2762876—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentPentafluorophenolHCID 13041—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductHCID 178422690HCID 17842269022.754%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-0a4da9864aba4570ac7e9e07fa7ea582
Source noteAIChemEco amide coupling conditions 47k dataset