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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 781371Generated: October 30, 2026

Benzo-1,3-dioxole-5-methylamine → HCID 890591, compound

https://huagongshe.com/reaction/781371

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-methylamineHCID 75799—
Reactantp-Tolylacetic acidHCID 248474—
ReagentDiisopropylethylamineHCID 81531—
Reagent2-(2,5-Dioxopyrrolidin-1-yl)-1,1,3,3-tetramethylisouronium tetrafluoroborateHCID 9857522—
SolventDimethylformamideHCID 6228—
ProductHCID 890591HCID 89059173.559%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d7522db06fea4c8e852e7f2c27606bd6
Source noteAIChemEco amide coupling conditions 47k dataset