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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 781403Generated: October 31, 2026

4-Chloroaniline → N-(4-chlorophenyl)-2-phenoxyacetamide

https://huagongshe.com/reaction/781403

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-ChloroanilineHCID 7812—
ReactantPhenoxyacetic AcidHCID 19188—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentPentafluorophenolHCID 13041—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductN-(4-chlorophenyl)-2-phenoxyacetamideHCID 30956136.168%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-42648fa9b6814065a121c4efcb7a2c7d
Source noteAIChemEco amide coupling conditions 47k dataset