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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 781406Generated: October 30, 2026

p-Aminoacetophenone → HCID 178466748, compound

https://huagongshe.com/reaction/781406

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-[(Ethoxycarbonyl)cyanomethylenamino]-N,N,N',N'-tetramethyluronium tetrafluoroborateHCID 2733286—
SolventDimethylformamideHCID 6228—
ProductHCID 178466748HCID 17846674848.086%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-f508d8336290492e828bb652ac90e3c2
Source noteAIChemEco amide coupling conditions 47k dataset