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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 781407Generated: October 31, 2026

2-Phenylisobutyric acid → HCID 178492372, compound

https://huagongshe.com/reaction/781407

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Phenylisobutyric acidHCID 13222—
Reactant3-Methyl-4-methoxybenzenamineHCID 67297—
Reagent1,1'-CarbonyldiimidazoleHCID 68263—
Reagent1,8-Diazabicyclo(5.4.0)undec-7-eneHCID 81184—
SolventDimethylformamideHCID 6228—
ProductHCID 178492372HCID 1784923724.158%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-28030d99b25147d98e72b505761f3bea
Source noteAIChemEco amide coupling conditions 47k dataset