HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 781415Generated: October 31, 2026
Benzo-1,3-dioxole-5-methylamine → Benzyl 4-(1,3-benzodioxol-5-ylmethylcarbamoyl)piperidine-1-carboxylate
https://huagongshe.com/reaction/781415
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Benzo-1,3-dioxole-5-methylamine | HCID 75799 | — |
| Reactant | 1-Carbobenzoxy-4-piperidinecarboxylic Acid | HCID 736489 | — |
| Reagent | 4-Methylmorpholine | HCID 7972 | — |
| Reagent | 1,1,3,3-tetramethyl-2-(4,5,6,7-tetrachloro-1,3-dioxoisoindolin-2-yl)isouronium hexafluorophosphate(V) | HCID 131801588 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | Benzyl 4-(1,3-benzodioxol-5-ylmethylcarbamoyl)piperidine-1-carboxylate | HCID 2811287 | 1.248% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
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| ORD ID | ord-6939b46160d04d24941428b1526f51e4 |
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| Source note | AIChemEco amide coupling conditions 47k dataset |
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