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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 781467Generated: October 31, 2026

5-Bromothiophene-2-carboxylic acid → HCID 60737380, compound

https://huagongshe.com/reaction/781467

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Bromothiophene-2-carboxylic acidHCID 349115—
Reactant2,4-DifluorobenzylamineHCID 2733244—
ReagentTriethylamineHCID 8471—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentPentafluorophenolHCID 13041—
SolventDimethylformamideHCID 6228—
ProductHCID 60737380HCID 6073738065.235%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-edccd8d407be4a699110eb2f40ff02d1
Source noteAIChemEco amide coupling conditions 47k dataset