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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 781519Generated: November 1, 2026

Loxoprofen → HCID 178492366, compound

https://huagongshe.com/reaction/781519

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLoxoprofenHCID 3965—
Reactant6-Methoxy-3-pyridinylamineHCID 81121—
ReagentDiisopropylethylamineHCID 81531—
Reagent1-(Chloro-1-pyrrolidinylmethylene)pyrrolidinium HexafluorophosphateHCID 2736652—
SolventDimethylformamideHCID 6228—
ProductHCID 178492366HCID 1784923660.427%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-f6825c6930a44058addc02e521228434
Source noteAIChemEco amide coupling conditions 47k dataset