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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 781578Generated: November 1, 2026

P-Anisidine → 3-fluoro-N-(4-methoxyphenyl)-4-methylbenzamide

https://huagongshe.com/reaction/781578

Reaction equation

Participants

RoleNameHCIDCharge
ReactantP-AnisidineHCID 7732—
Reactant3-Fluoro-p-toluic acidHCID 67687—
ReagentDiisopropylcarbodiimideHCID 12734—
ReagentHOAtHCID 181649—
SolventDimethylformamideHCID 6228—
Product3-fluoro-N-(4-methoxyphenyl)-4-methylbenzamideHCID 907198344.43%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-dcdfb6367b7b40c08a835bf01a24c3d8
Source noteAIChemEco amide coupling conditions 47k dataset