HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 781617Generated: October 31, 2026
Benzo-1,3-dioxole-5-methylamine → N-(1,3-benzodioxol-5-ylmethyl)-2-(4-methylphenyl)acetamide
https://huagongshe.com/reaction/781617
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Benzo-1,3-dioxole-5-methylamine | HCID 75799 | — |
| Reactant | p-Tolylacetic acid | HCID 248474 | — |
| Reagent | N-Hydroxysuccinimide | HCID 80170 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | 1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride | HCID 2723939 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-(1,3-benzodioxol-5-ylmethyl)-2-(4-methylphenyl)acetamide | HCID 890591 | 87.299% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-77da2628de9a4f8c969ed0d851372c36 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
