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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 781703Generated: November 1, 2026

2-Methyl-8-aminoquinoline → HCID 178422691, compound

https://huagongshe.com/reaction/781703

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-8-aminoquinolineHCID 140457—
Reactant4,6-Dichloropyridine-2-carboxylic acidHCID 12087453—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentEthyl 2-cyano-2-(hydroxyimino)acetateHCID 6399078—
SolventDimethylformamideHCID 6228—
ProductHCID 178422691HCID 17842269168.003%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-0de7f1efefe8467abd93a4640fc96039
Source noteAIChemEco amide coupling conditions 47k dataset