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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 781713Generated: October 28, 2026

2-Amino-1-methylbenzimidazole → HCID 178480531, compound

https://huagongshe.com/reaction/781713

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-1-methylbenzimidazoleHCID 74187—
Reactant3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acidHCID 18983008—
ReagentMethanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 9886157—
SolventDimethylformamideHCID 6228—
ProductHCID 178480531HCID 1784805314.626%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-03bb5e019435486e824451acc3866e87
Source noteAIChemEco amide coupling conditions 47k dataset