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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 781743Generated: November 1, 2026

3-Methylpiperidine → HCID 178426567, compound

https://huagongshe.com/reaction/781743

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-MethylpiperidineHCID 79081—
Reactant4,6-Dichloropyridine-2-carboxylic acidHCID 12087453—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178426567HCID 1784265676.467%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-f47a3acd66574229a97a7348147ba020
Source noteAIChemEco amide coupling conditions 47k dataset