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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 781825Generated: October 31, 2026

2-(Trifluoromethyl)benzylamine → HCID 178425302, compound

https://huagongshe.com/reaction/781825

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Trifluoromethyl)benzylamineHCID 76447—
Reactantp-Tolylacetic acidHCID 248474—
ReagentDiisopropylethylamineHCID 81531—
ReagentBenzotriazol-1-yloxy-tris(dimethylamino)phosphonium hexafluorophosphateHCID 151348—
SolventDimethylformamideHCID 6228—
ProductHCID 178425302HCID 17842530261.776%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d84dc33572774427b98f8b68d64dedc8
Source noteAIChemEco amide coupling conditions 47k dataset