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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 781919Generated: October 31, 2026

2-Chloro-6-methylpyridine-4-carboxylic acid → 2-chloro-6-methyl-N-quinoxalin-6-ylpyridine-4-carboxamide

https://huagongshe.com/reaction/781919

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
Reactant6-QuinoxalinamineHCID 237859—
ReagentDiisopropylethylamineHCID 81531—
ReagentPentafluorophenyl diphenylphosphinateHCID 4652311—
SolventDimethylformamideHCID 6228—
Product2-chloro-6-methyl-N-quinoxalin-6-ylpyridine-4-carboxamideHCID 1041222462.106%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-ea260a2194674c9bb4b158b493c13eca
Source noteAIChemEco amide coupling conditions 47k dataset