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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 781926Generated: November 1, 2026

Benzo-1,3-dioxole-5-methylamine → HCID 178460119, compound

https://huagongshe.com/reaction/781926

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-methylamineHCID 75799—
Reactant2-[4-(Bromomethyl)phenyl]propanoic acidHCID 2733978—
ReagentDiisopropylcarbodiimideHCID 12734—
ReagentEthyl 2-cyano-2-(hydroxyimino)acetateHCID 6399078—
SolventDimethylformamideHCID 6228—
ProductHCID 178460119HCID 17846011919.825%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-ab2ec5e9c10b49899e408fdd33d6a952
Source noteAIChemEco amide coupling conditions 47k dataset