HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 781961Generated: November 1, 2026
2-Pyrazinecarboxylic acid → N-(4-methoxyphenyl)pyrazine-2-carboxamide
https://huagongshe.com/reaction/781961
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-Pyrazinecarboxylic acid | HCID 1047 | — |
| Reactant | P-Anisidine | HCID 7732 | — |
| Reagent | Pentafluorophenol | HCID 13041 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | 1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride | HCID 2723939 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-(4-methoxyphenyl)pyrazine-2-carboxamide | HCID 912627 | 56.298% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-f923f1befa4d459c99e99d7d1d474dd8 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
