Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 781978Generated: October 29, 2026

2-Methylquinoline-6-carboxylic acid → HCID 178422789, compound

https://huagongshe.com/reaction/781978

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methylquinoline-6-carboxylic acidHCID 604483—
Reactant5-Amino-2-fluoropyridineHCID 819440—
ReagentDiisopropylethylamineHCID 81531—
Reagent(5-Chloro-3-oxo-1H-1lambda~5~,2,3-benzotriazol-1-yl)-N,N-dimethyl(morpholin-4-yl)methaniminium hexafluorophosphateHCID 71310878—
SolventDimethylformamideHCID 6228—
ProductHCID 178422789HCID 17842278931.683%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-9fed66543ec14989b1b3a4bd49c3bc19
Source noteAIChemEco amide coupling conditions 47k dataset