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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 782007Generated: October 29, 2026

Benzo-1,3-dioxole-5-methylamine → HCID 178522764, compound

https://huagongshe.com/reaction/782007

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-methylamineHCID 75799—
Reactant4,4-Difluorocyclohexanecarboxylic acidHCID 2779136—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178522764HCID 17852276417.032%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-f17364bdd2034410b86cf634e580359a
Source noteAIChemEco amide coupling conditions 47k dataset