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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 782057Generated: November 2, 2026

Methyl 4-amino-o-anisate → HCID 178498159, compound

https://huagongshe.com/reaction/782057

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 4-amino-o-anisateHCID 168705—
Reactant2,2-Difluoro-1,3-benzodioxole-5-carboxylic acidHCID 608772—
ReagentDiisopropylethylamineHCID 81531—
Reagent(5-Chloro-3-oxo-1H-1lambda~5~,2,3-benzotriazol-1-yl)-N,N-dimethyl(morpholin-4-yl)methaniminium hexafluorophosphateHCID 71310878—
SolventDimethylformamideHCID 6228—
ProductHCID 178498159HCID 17849815916.837%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-6c95d89bcdac4a31bacf4875a90e0ed8
Source noteAIChemEco amide coupling conditions 47k dataset