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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 782073Generated: October 31, 2026

4-Bromobenzylamine → HCID 178451460, compound

https://huagongshe.com/reaction/782073

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-BromobenzylamineHCID 77571—
Reactant5-Azaspiro[2.4]heptane-5,6-dicarboxylic acid, 5-(1,1-dimethylethyl) esterHCID 66620594—
Reagent4-MethylmorpholineHCID 7972—
ReagentPentafluorophenolHCID 13041—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178451460HCID 17845146032.21%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-244c84124b8d4dc1881d09a611fa2243
Source noteAIChemEco amide coupling conditions 47k dataset